Kirin Supplement Series Performs Strongly in January–March, Posting Approximately 10% Year-on-Year Sales Growth and Exceeding Market Expectations

Key Factors Behind the Strong Performance

1. Rising Year-Round Health Awareness Among Consumers

In recent years, consumers’ health consciousness has continued to rise, with more people becoming mindful of managing their physical condition on a daily basis.
Against this backdrop, Kirin has consistently communicated the importance of practicing health management as a year-round habit rather than seasonal effort. As a result, the Kirin iMUSE Immune Care Supplement series has begun to see the establishment of “immune care*3” as a routine practice, supported by the expansion of repeat purchases.
Similarly, the Kirin Ornithine series has seen broader usage as products that address a wide range of health concerns faced by consumers and is expected to become increasingly integrated into everyday life going forward.
3 Supporting the maintenance of immune function in healthy people (research report on LC-Plasma)

2. Expanded Awareness and New Customer Acquisition Through Promotional Communication

Planned and enhanced promotional communication during the January–March period contributed to increased awareness of the Kirin supplement series.
By leveraging all channels—including Kirin’s own direct-to-consumer platform, external e-commerce platforms, and retail distribution—and deploying communications tailored to each product’s characteristics and target audience, Kirin successfully reached consumer segments with limited prior exposure to supplements, driving new customer acquisition.
In addition, cross-channel communication successfully combined awareness-building with habit-formation messaging, contributing to a steady increase in subscription customers and an overall uplift in demand.

About the Kirin iMUSE Immune Care Supplement Series

Sales value for the overall iMUSE Immune Care Supplement series, which contains Kirin’s proprietary ingredient LC-Plasma, increased by approximately 10% year on year.
Promotional communication, including campaigns featuring professional baseball player Shohei Ohtani as an “Immune Care” promotion ambassador*4, contributed to expanded awareness, with brand recognition increasing to approximately 1.2 times the previous year*5. In addition, the number of customers who purchased within the past three months increased to approximately 1.3 times year on year*6, indicating an expansion of the new customer base.
The newly launched “Kirin iMUSE Immune Care and subjective fatigue relief” in February 2026 is also performing steadily against its full-year sales targets. Expansion of the product lineup to meet increasingly diverse consumer health needs is contributing to growth across the entire series.
4 Shohei Ohtani Appointed as Kirin's "Immune Care" Promotion Ambassador "I hope that through immune care, more people will become and stay healthy." | 2025 | KIRIN - Kirin Holdings Company, Limited
5.6 Kirin survey (n=10,000).

About Kirin’s Proprietary Ingredient “LC-Plasma”

LC-Plasma is a lactic acid bacteria that support the maintenance of immune function in healthy individuals. They are the first in the world*7 to be reported in academic papers to act on pDCs (plasmacytoid dendritic cells), known as the command center of the immune system. Kirin Holdings, KOIWAI DAIRY PRODUCTS CO., LTD., and KYOWA HAKKO BIO CO., LTD. have jointly conducted research on this product, and with the cooperation of universities and research institutions in Japan and overseas, 37 papers have been published and numerous presentations made at academic conferences.*8
7 LC-Plasma was the first lactic acid bacteria reported to work on pDCs in humans (based on information published in PubMed and the homepage of the Central Medical Journal).
8 As of April 30, 2026.

About the Kirin Ornithine Series

Sales value for the overall KIRIN Ornithine series increased by approximately 20% year on year, demonstrating strong performance.
In addition to the renewal of Kirin Ornithine PRO Sleep & Immune Care in June 2025, strengthened digital promotional activities tailored to the target audience expanded awareness and contributed to new customer acquisition.
The KIRIN Ornithine PRO Fatigue & Mood Care plus Sleep Quality, launched in December 2025, exceeded expectations, with January–March sales reaching approximately 2.2 times the planned level.
By being easy to incorporate into busy daily routines and addressing consumer needs for relief from fatigue and mental well-being, the product drove strong sales performance and contributed to the overall growth of the series.
Through the Kirin Ornithine series, Kirin will continue to support consumers leading busy lives by proposing sustainable health habits that can be naturally maintained in everyday life.

About Ornithine

Ornithine is a health ingredient known for being abundant in clams. Unlike typical amino acids that constitute proteins, ornithine is a unique amino acid that circulates independently within the body to exert its functions.
Kyowa Hakko Bio Co., Ltd., a Kirin Group company, became the world’s first to achieve large-scale production of amino acids via fermentation in 1956. Since then, the Kirin Group has conducted more than half a century of research and development into ornithine and other amino acids.

Functional foods
[Kirin iMUSE Immune Care Supplement]
[Reported indication]
This product contains LC-Plasma (L. lactis strain Plasma). LC-Plasma acts on pDCs (plasmacytoid dendritic cells) and has been reported to help maintain immune function in healthy people.

[Kirin iMUSE Immune Care and subjective fatigue relief]
[Reported indication]
This product contains LC-Plasma (L. lactis strain Plasma). LC-Plasma acts on pDCs (plasmacytoid dendritic cells) and has been reported to help maintain immune function in healthy people.
This product also contains reduced coenzyme Q10, which has been reported to help relief subjective fatigue in individuals who experience fatigue in daily life.

[Kirin Ornithine PRO Sleep & Immune Care]
[Reported indication]
This product contains L-ornithine hydrochloride (L-ornithine), which has been reported to support improvements in sleep quality (ease of falling asleep, depth of sleep, and a refreshed feeling upon waking).
This product contains LC-Plasma (L. lactis strain Plasma). LC-Plasma acts on pDCs (plasmacytoid dendritic cells) and has been reported to help maintain immune function in healthy people.

[KIRIN Ornithine PRO Fatigue & Mood Care plus Sleep Quality]
[Reported indication]
This product contains L-ornithine monohydrochloride (L-ornithine), which has been reported to help reduce temporary fatigue and psychological stress in daily life, support a calm feeling the next morning, and improve sleep quality (ease of falling asleep, depth of sleep, and a refreshed feeling upon waking).

Notes:
1 Diet should include staple foods, main dishes, and side dishes for a balanced diet.
2 Unlike Foods for Specified Health Uses (FOSHU), this product has not been evaluated by the government for its functionality or safety. Information on the scientific evidence submitted can be found on the Consumer Affairs Agency website.
3 This product is not a pharmaceutical product.