Kirin iMUSE Supplement Series Containing L. lactis Plasma Achieves Record-High January-June Sales Revenue, Up Approximately 20% Year-on-Year

Factors Behind the Strong Performance

1. Rising Consumer Interest in Health Management Throughout the Year

In recent years, health consciousness among consumers has continued to grow, with more people seeking to manage their physical condition on an ongoing basis in their daily lives. In response, the Company strengthened its communications regarding the importance of incorporating “immune care”*2 into everyday health habits.
As a result, monthly sales revenue for the series has exceeded the previous year’s level every month since February 2026. This trend suggests that “immune care” is becoming established among consumers not merely as a temporary measure for maintaining physical condition, but as a daily health habit that supports healthy living.
In addition, according to the Japan Meteorological Agency’s warm-season forecast, this summer is expected to be dominated by warm air masses, resulting in higher-than-normal temperatures across Japan.*3 Interest in daily health management is expected to increase further during prolonged periods of heat, leading to additional growth in demand for “immune care.”
*2 Supporting the maintenance of immune function in healthy people (research report on L. lactis Plasma).
*3 Japan Meteorological Agency, “Seasonal Forecast Commentary Materials (Warm-Season Forecast, announced February 24, 2026).”

2. Expanded Awareness and Purchase Opportunities Drove New Customer Acquisition and Habit Formation

The Company continuously implemented communications throughout the year to highlight the importance of immune care, including promotional campaigns featuring Shohei Ohtani as the “Immune Care” Promotion Ambassador.*4 These activities significantly increased awareness of the series. In addition, the Company expanded consumer touchpoints through its direct-to-consumer channels, external e-commerce platforms, and retail distribution channels, tailoring communications to product characteristics and target consumer groups.
As a result of these initiatives, purchase touchpoints through both direct-to-consumer and external e-commerce channels, as well as retail distribution channels, increased by approximately 10% year-on-year. This expansion enabled the Company to reach previously untapped consumer segments and acquire new customers.*5 The combination of greater awareness and expanded purchase opportunities helped position immune care as an easy-to-maintain daily health habit, contributing to overall sales growth across the series.
*4 Shohei Ohtani Appointed as Kirin's "Immune Care" Promotion Ambassador "I hope that through immune care, more people will become and stay healthy." | 2025 | KIRIN - Kirin Holdings Company, Limited
*5 Based on the Company’s analysis of TRUE DATA’s “Eagle Eye” data comparing purchase touchpoints for the “Kirin iMUSE Supplement” series at drugstores nationwide during January-June 2026 versus the same period of the previous year.

About the “Kirin iMUSE Supplement” Series

Sales value of Kirin iMUSE Immune Care Supplement (7-day, 15-day, 30-day, and 60-day packs) exceeded the previous year’s level and continued to perform steadily.
In addition, “Kirin iMUSE Immune Care & Visceral Fat Down”, a product in the W Care series that addresses health concerns of high interest to consumers while centering on “immune care,” achieved strong growth, with sales value increasing by approximately 60% year-on-year. In addition to consumers’ daily health management needs, the product successfully addressed multiple health needs, including concerns about visceral fat, *6 which contributed to its strong sales performance.
*6 Studies have reported that kudzu flower-derived isoflavones (as tectorigenin compounds) help reduce body weight, abdominal fat (visceral and subcutaneous fat), and waist circumference in overweight individuals. “Overweight individuals” refers to those with a BMI of 25 or higher but less than 30.

About L. lactis Plasma

L. lactis Plasma is a heat-killed lactic acid bacteria that supports the maintenance of immunity in healthy people. It has been reported in research papers that it is the first in the world*7 to work on pDCs (plasmacytoid dendritic cells), a leader of the immune system. Kirin Holdings, KOIWAI DAIRY PRODUCTS CO., LTD., and KYOWA HAKKO BIO CO., LTD. have jointly conducted research on this product, and with the cooperation of universities and research institutions in Japan and overseas, 38 papers have been published and numerous presentations made at academic conferences.*8
7 L. lactis Plasma was the first lactic acid bacteria reported to work on pDCs in humans (based on information published in PubMed and the homepage of the Central Medical Journal).
8 As of July 31, 2026.

Food with functional claims
[Kirin iMUSE Immune Care Supplement]
[Reported indication]
This product contains LC-Plasma (L. lactis strain Plasma). LC-Plasma acts on pDCs (plasmacytoid dendritic cells) and has been reported to help maintain immune function in healthy people.

[Kirin iMUSE Immune Care & Visceral Fat Down]
[Reported indication]
This product contains LC-Plasma (L. lactis strain Plasma). Studies have reported that LC-Plasma acts on plasmacytoid dendritic cells (pDCs) and helps maintain immune function in healthy individuals.
This product also contains kudzu flower-derived isoflavones (as tectorigenin compounds). These ingredients have been reported to help reduce body weight, abdominal fat (visceral and subcutaneous fat), and waist circumference in overweight individuals.

Notes:
1 Diet should include staple foods, main dishes, and side dishes for a balanced diet.
2 Unlike Foods for Specified Health Uses (FOSHU), this product has not been evaluated by the government for its functionality or safety. Information on the scientific evidence submitted can be found on the Consumer Affairs Agency website.
3 This product is not a pharmaceutical product.